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Jerktonium
The Jerktonium only appears in It's a SpongeBob Christmas!. It is a chemical element in the periodic table discovered by Plankton. He includes it in the fruitcake that is given out to everybody in Bikini Bottom. The Jerktonium causes all Bikini Bottomites to become grumpy in order to make Plankton appear to be the nicest of them all. Everyone who tries the fruitcake gets big black and bushy eyebrows. Plankton's first victim is SpongeBob who is immune to the Jerktonium because he has a pure heart. Soon Plankton gets tired and allows SpongeBob to deliver the fruitcake so everybody gets infected with Jerktonium.
